Post-Exposure Prophylaxis (PEP) for HIV Guidelines


First Published:
Last Updated:
June 2023
Resource Type:


June 2023: The Third edition of the Post-Exposure Prophylaxis after Non-Occupational and Occupational Exposure to HIV: Australian National Guidelines is available.

These guidelines outline the updated Australian recommendations for human immunodeficiency virus (HIV) post-exposure prophylaxis (PEP) following potential or known exposure to HIV in sexual, occupational, and non-occupational settings. Risk of transmission, the timing of PEP, baseline assessment, preferred regimen and follow-up are outlined. Some sections of the guideline, which are longer or more complex, have a quick reference summary under the heading Key recommendations.

These guidelines are not intended to be prescriptive or replace specialist advice in the provision of PEP. Every presentation for PEP should be assessed on a case-by-case basis, balancing the potential harms and benefits of treatment.

Visit the website version of the guidelines

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